Table 1.
Demographics of the study population.
| Database 1-Discovery (N = 1245) | Database 2-Replication (N = 840) | Database 3-Total (N = 2085) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Controls (N = 996) |
Cases (N = 249) |
p Value | Controls (N = 676) |
Cases (N = 164) |
p Value | Controls (N = 1672) |
Cases (N = 413) |
p Value | |
| Age | 48.16 (9.92) | 48.01 (9.43) | 0.827 | 47.84 (11.00) | 47.92 (10.91) | 0.934 | 48.03 (10.37) | 47.98 (10.03) | 0.919 |
| Gender | 1.000 | 0.924 | 0.939 | ||||||
| Female | 228 (22.9) | 57 (22.9) | 188 (27.8) | 45 (27.4) | 416 (24.9) | 102 (24.7) | |||
| Male | 768 (77.1) | 192 (77.1) | 488 (72.2) | 119 (72.6) | 1256 (75.1) | 311 (75.3) | |||
| Alcohol users | <0.001 ** | <0.001 ** | <0.001 ** | ||||||
| No | 830 (83.4) | 156 (62.7) | 581 (85.9) | 105 (64.0) | 1411 (84.4) | 261 (63.2) | |||
| Yes | 165 (16.6) | 93 (37.3) | 95 (14.1) | 59 (36.0) | 260 (15.6) | 152 (36.8) | |||
| Betel quid chewers | <0.001 ** | <0.001 ** | <0.001 ** | ||||||
| No | 937 (94.3) | 189 (75.9) | 631 (93.6) | 129 (78.7) | 1568 (94.0) | 318 (77.0) | |||
| Yes | 57 (5.7) | 60 (24.1) | 43 (6.4) | 35 (21.3) | 100 (6.0) | 95 (23.0) | |||
| Cigarette smokers | 0.005 * | <0.001 ** | <0.001 ** | ||||||
| No | 620 (62.3) | 131 (52.6) | 464 (68.6) | 80 (48.8) | 1084 (64.9) | 211 (51.1) | |||
| Yes | 375 (37.7) | 118 (47.4) | 212 (31.4) | 84 (51.2) | 587 (35.1) | 202 (48.9) | |||
Values are presented as N (%) or mean (SD). p values for chi square test or two independent t-tests: * represent p values less than 0.05; ** represent p values less than 0.001.