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. 2021 Oct 19;9(10):1397. doi: 10.3390/healthcare9101397

Table 2.

Characteristics of the included studies.

Study Study Groups Study Intervention Study Duration Training Protocol
Clark [28] Conventional resistance training (CO): 26; Control (CG): 17 CO: 8 exercises (chest press, body squat, squat calf, lat machine, arm curls, leg press, knee extension, knee flexion) with weights.
CG: No intervention.
12 weeks Frequency: 2 d/w
Reps: 3 × 10
Phase velocity: NA
Rest: NA
Load: 70% of 1RM
Progression: Every 6 weeks (repeating 1RM test)
Dourado [29] Conventional resistance training (CO): 11; Low-intensity training (LIT): 13; Combined training (CT): 11 CO: 7 exercises (leg press, leg extension, lat pull down, chest press, seated rowing, triceps pulley, and biceps curl) with weight machines.
LIT: 30 min of walking and 30 min of low-intensity CO with free weights, on exercise mats and on parallel bars.
CT: 30 min of CO group and 30 min as LIT group.
12 weeks Frequency: 3 d/w
Reps: 3 × 12 (CO); 2 × 8 (CT)
Phase velocity: NA
Rest: 2 min
Load: 50–80% of 1RM
Progression: Every 3 weeks (repeating 1RM test)
Freire [41] Conventional resistance training (CO): 16; Elastic tubing resistance (ER): 18; Elastic bands resistance (EB): 14 CO: 5 exercises (shoulder abduction, elbow flexion, shoulder flexion; knee extension and knee flexion) with weight machines.
ER and EB: The same exercise program of CO was carried out with elastic tubing or bands.
12 weeks Frequency: 3 d/w
Reps: 2 × 15 (weeks 1–2); 3 × 15 (weeks 3–6); 3 × 10 (weeks 7–9); 3 × 15 (weeks 10–12)
Phase velocity: 2 s
Rest: 2 min
Load: established with nRM
Progression: Each session with the nRM test
Hoff [35] Conventional resistance training (CO): 6; Control (CG): 6 CO: 1 exercise (leg press).
CG: No intervention.
8 weeks Frequency: 3 d/w
Reps: 4 × 5
Phase velocity: Explosive concentric, slow eccentric
Rest: 2 min
Load: 85–90% of 1RM
Progression: 2.5 kg increment when 5 reps were exceeded
Kongsgaard [30] Conventional resistance training (CO): 6; Control (CG): 7 CO: 3 exercises (leg press, knee extension, knee flexion) with weight machines.
CG: Breathing exercise.
12 weeks Frequency: 2 d/w
Reps: 4 × 8
Phase velocity: Explosive concentric
Rest: 2–3 min
Load: 80% of 1RM
Progression: Every week
Nyberg [36] Elastic bands resistance (EB): 22; Control (CG): 22 EB: 8 exercises (latissimus row, chest press, leg extension, straight arm shoulder flex, leg curl, elbow flexion, leg heel raise, leg step-up).
CG: 4 days of education.
8 weeks Frequency: 3 d/w
Reps: 2 × 25
Phase velocity: 1 s
Rest: 1 min
Load: Established nRM
Progression: Every 2 sessions (if Borg scale < 4)
Nyberg [42] Elastic band single-limb resistance (SEB): 16; Elastic band two-limb resistance (TEB):17 SEB: 7 exercises (knee extension, leg curl, latissimus row, chest press, elbow flexion, shoulder flexion, calf) with a single limb at a time.
TEB: As SEB but using both limbs at a time.
8 weeks Frequency: 3 d/w
Reps: 3 × 25–30
Phase velocity: 1 s
Rest: 1 min
Load: Established nRM
Progression: Increased every two sessions by 10% if patients exceeded 30 reps
Ortega [31] Conventional resistance training (CO): 17; Endurance training (ET): 16; Combined training (CT): 14 CO: 5 exercises (lat pull, butterfly, neck press, leg flexion, leg extension) with gymnastic apparatus.
ET: 40 min of cycling at 70% of peak work capacity.
CT: 20 min of cycling plus CO.
12 weeks Frequency: 3 d/w
Reps: 4 × 6–8 (CO); 2 × 6–8 (CT)
Phase velocity: NA
Rest: NA
Load: 70–85% of 1RM
Progression: Every 2 weeks (repeating 1RM test)
Ramos [37] Conventional resistance training (CO): 17; Elastic tubing resistance (ER): 17 CO: 5 exercises (knee extension, knee flexion, shoulder abduction, shoulder flexion, elbow flexion) with weight machines.
ER: Same exercises as CO group, performed with elastic tubing.
8 weeks Frequency: 3 d/w
Reps: 3 × 10 (CO); 2–7 × maximum in 20 s (ER)
Phase velocity: NA
Rest: 2 min
Load: 60% (week 1) to 80% (week 8) of 1RM
Progression: Increased by 4% every four sessions (CO); increased by one set every two sessions (ER)
Silva [32] Conventional resistance training (CO): 10; Elastic tubing resistance (ER): 9 CO: 5 exercises (knee flexion, knee extension, shoulder flexion, shoulder abduction, elbow flexion) with weight machines.
ER: Same exercises as CO group, performed with elastic tubing.
12 weeks Frequency: 3 d/w
Reps: 2 × 15 (weeks 1–3); 3 × 15 (weeks 4–6); 3 × 10 (weeks 7–9); 4 × 6 (weeks 10–12)
Phase velocity: 1.8 s
Rest: 2 min
Load: 15RM
Progression: Increased when patients exceeded the nRM
Silva [33] Conventional resistance training (CO): 11; Elastic resistance (ER): 24 CO: 5 exercises (knee flexion, knee extension, shoulder flexion, shoulder abduction, elbow flexion) with weight machines.
ER: Same exercises as CO group, performed with elastics.
12 weeks Frequency: 3 d/w
Reps: 2 × 15 (weeks 1–3); 3 × 15 (weeks 4–6); 3 × 10 (weeks 7–9); 3 × 15 (weeks 10–12)
Phase velocity: NA
Rest: NA
Load: Established nRM
Progression: Increased when patients exceeded the nRM
Simpson [38] Conventional resistance training (CO): 14; Control (CG): 14 CO: 3 exercises with weights using a single limb at a time (arm curl, leg extension, leg press).
CG: No intervention.
8 weeks Frequency: 3 d/w
Reps: 3 × 10
Phase velocity: Slow concentric
Rest: NA
Load: 50% (week 1) to 85% (week 8) of 1RM
Progression: Every 6 sessions (repeating 1RM test)
Spruit [39] Conventional resistance training (CO): 14; Endurance training (ET): 16 CO: 6 exercises (quadriceps, pectorals, triceps brachia, deltoids, biceps brachia, hamstrings) with weight machines.
ET: Cycling or walking for 25 min at 75% of peak work or 60% of 6-min walk speed) plus arm cranking (4–9 min).
12 weeks Frequency: 3 d/w
Reps: 3 × 8
Phase velocity: NA
Rest: NA
Load: 70% of 1RM
Progression: Increased by 5% of 1RM every week
Vonbank [34] Conventional resistance training (CO): 12; Endurance training (ET): 12; Combined training (CT): 12 CO: 8 exercises (chest press, chest cross, shoulder press, pull downs, biceps curl, triceps extensions, sit-ups, leg press).
ET: Cycling for 20 min (increased by 5 min every 4 weeks) at 60% of estimated VO2peak.
CT: CO plus ET
12 weeks Frequency: 2 d/w
Reps: 2 × 8–15 (weeks 1–4); 3 × 8-15 (weeks 5–9); 4 × 8–15 (weeks 10–12)
Phase velocity: NA
Rest: NA
Load: Established nRM
Progression: Increased when patients exceeded the nRM
Zambom-
Ferraresi [40]
Conventional resistance training (CO): 14; Combined training (CT): 14; Control (CG): 8 CO: 6 exercises (leg press, knee extension, knee flexion, chest press, seated row, shoulder press) with weight machines.
CT: one d/w of CO and 1 d/w of cycling for 20–35 min at 65–90% of peak heaCO rate (increased each session).
CG: No intervention.
12 weeks Frequency: 2 d/w
Reps: 3–4 × 6–12
Phase velocity: NA
Rest: NA
Load: 50–70% of 1RM
Progression: Every 6 weeks (repeating 1RM test)

1RM, one repetition maximum; 15RM, fifteen maximal repetitions; CG, control group; CO, conventional resistance training; CT, combined training; EB, resistance training with elastic bands; ER, resistance training with elastic tubing; ET, endurance training; LIT, low-intensity training; NA, not applicable; nRM, maximum number of repetitions; SEB, single-limb resistance training; TEB, two-limb resistance training.