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. 2021 Sep 29;12(10):1548. doi: 10.3390/genes12101548

Table 1.

Expression levels of cyclins, cyclin-dependent kinases (CDKs) and phosphorylation status of retinoblastoma protein (RB) in mESCs and hESCs during cell cycle progression.

mESCs hESCs
Cyclin expression levels
Cyclin A/E High, non-oscillatory High, oscillatory
Cyclin B High, oscillatory High, oscillatory
Cyclin D Low, oscillatory Intermediate, oscillatory
CDKs expression levels
CDK1 High, oscillatory High, oscillatory
CDK2 High, non-oscillatory High, oscillatory
CDK4 Low, oscillatory Medium, oscillatory
CDK6 Medium, oscillatory Low, oscillatory
RB phosphorylation
RB Hyper-phosphorylated Hypo-/Hyper-phosphorylated