Figure 2.
Analyses of cell migration and invasion in MDA-MB-468 cells transfected with siHOXB7 and control siNEG. Wound-healing assays suggest reduced capacity to migrate in HOXB7-silenced cells, detectable after 16h post-transfection (A). Transwell filter-based assays also point to lower migration and invasion abilities in HOXB7-silenced cells than in the controls (B). Three independent biological replicates were used in the statistical analyses, and significant differences are indicated with asterisks (*, p < 0.001; **, p < 0.05), based on t-test analyses.