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Alcohol consumption on Day 4 was associated with an increase in the expression of circadian genes in the NAcSh. Mice exposed to four days of binge alcohol consumption (N = 5) displayed a significant increase in the expression of Per1 (Panel A & D), Per2 (Panel B & E) and Clock (Panel C & F) genes into the nucleus accumbens (NAcSh) and suprachiasmatic nucleus (SCN) as compared to the mice exposed to sucrose (N = 5). **p < 0.01 and ***p<0.001 vs Sucrose.
