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. 2021 Sep 28;12(10):1539. doi: 10.3390/genes12101539

Table 1.

Commercial methylation kits for colorectal cancer detection.

Manufacture Product Name Target Genes Specimen Type Sensitivity/Specificity for CRC 1
Exact Sciences Cologuard NDRG4, BMP3 Stool DNA 92%/90%
Epigenomics Epi proColon SEPT9 Plasma DNA 68%/89%
New Horizon Health Limited ColoClear NDRG4, BMP3 Stool DNA 96%/87%
BGI Genomics Colotect ADHFE1, SDC2, PPP2R5C Stool DNA 90%/89%
Ammunition Life Technology IColocomf SDC2, TFPI2 Stool DNA 93%/95%
Creative Biosciences Colosafe SDC2 Stool DNA 84%/98%
BioChain Institute mSEPT9 SEPT9 Plasma DNA 77%/86%
RealBio Technology COLOWELL SDC2, SFRP2 Stool DNA 84%/94%

1 Sensitivity and specificity values were provided by manufacturer instructions or published articles.