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. 2021 Oct 22;7(43):eabj3627. doi: 10.1126/sciadv.abj3627

Fig. 5. Differences in cytokine and chemokine levels in serum, BAL, and nose samples of rhesus macaques inoculated with D614G, B.1.1.7, or B.1.351.

Fig. 5.

Three groups of six adult rhesus macaques were inoculated with SARS-CoV-2 variants D614G, B.1.1.7, or B.1.351. The levels of 10 cytokines and chemokines were determined in serum on 0, 2, 4, and 6 dpi (A); in BAL on 2 and 4 dpi (B); and in nasal samples on 0, 2, 4, and 6 dpi (C). For serum and nasal samples, fold change in cytokine/chemokine level is shown normalized to baseline levels measured on 0 dpi. For BAL samples, concentrations are shown. Data represent the mean log2 fold change or concentration of analytes in variant groups at each time point and are organized according to unsupervised hierarchical clustering.