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. 2021 Sep 28;12(10):1527. doi: 10.3390/genes12101527

Table 1.

Function of two-component system in Staphylococcus aureus MW2 strain.

TCS no. Gene Name Gene ID Function
TCS1 vicRS MW0018-19 Cell division/separation, lethal
TCS2 htpRS MW0198-99 response to extracellular phosphates and survival/multiplication within host cells
TCS3 lytSR MW0236-37 Lytic enzymes
TCS4 apsRS, graRS MW0621-22 Bacterial surface charge, dltABCD, mprF
TCS5 saeRS MW0667-68 Virulence factor expression
TCS6 - MW1208-09 No report
TCS7 arlRS MW1304-05 Virulence factor expression
TCS8 srrAB MW1445-46 Oxidative stress
TCS9 phoPR MW1636-37 inorganic phosphate uptake
TCS10 - MW1789-90 No report
TCS11 vraSR MW1824-25 Resistant against cell wall synthesis inhibitor
TCS12 agrCA MW1962-63 quorum sensing, virulence factor expression
TCS13 kdpDE MW2002-03 Neutrophil sensitivity
TCS14 hssRS MW2282-83 Iron efflux
TCS15 nreCB MW2313-14 nitrate respiration
TCS16 bceRS, braRS MW2544-45 Bacteriocin resistance