Correlation plot of the difference between vitamin D concentration and genetic risk score using related single-nucleotide polymorphisms or latitude. (a) The difference between vitamin D and genetic risk score, showing that a lower genetic risk score cannot compensate or generate vitamin D when this population is relocated to a higher latitude, where the regression R2 is 0.9996. (b) Difference between vitamin D and latitude, showing that latitude difference does not impact the difference of vitamin D as much as genetic risk score, with an R2 value of 0.6538. (AFR: African, AMR: American, EAS: East Asian).