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. 2021 Aug 26;118(35):e2107673118. doi: 10.1073/pnas.2107673118

Fig. 1.

Fig. 1.

Mn exposure increases SLC30A10 expression in the liver of 129S4/SvJaeJ and intestines of C57BL/6J mice. qRT-PCR analyses from indicated tissues of 129S4/SvJaeJ or C57BL/6J mice treated with vehicle or oral Mn (∼15 mg absolute Mn/kg body weight daily) from PND1 until 8 wk of age. Animals were euthanized at 8 wk of age. For each strain, the mean expression in vehicle-treated mice was normalized to 1. n = 10 vehicle and 12 Mn for 129S4/SvJaeJ, and 7 vehicle and 8 Mn for C57BL/6J mice. Mean ± SE, *P < 0.05 by two-way ANOVA (strain and Mn treatment as independent variables) and Sidak’s post hoc test for indicated comparisons; n.s., not significant.