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Effects of MSCs-Exo on CLP-induced mice sepsis model in vivo. (a) The survival rate of CLP-mice was significantly improved via MSCs-Exo treatment. (b) The release levels of LDH and CK in CLP-mice and CLP-mice treated with MSCs-Exo were measured by LDH detection kit and CK detection kit, respectively. (c) Hematoxylin and eosin staining in CLP-treated mice. ∗∗P < 0.01, ∗∗∗P < 0.001, #P < 0.05, ###P < 0.001 vs. the control group.
