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. 2021 Oct 15;2021:1530445. doi: 10.1155/2021/1530445

Figure 4.

Figure 4

MiR-146a-5p is the potential target of MSCs-Exo in sepsis. (a) The comparative toxicogenomics database and GeneCards database were used to identify the potential target of MSCs-Exo. (b) The profiler cluster analysis was employed to select gene with higher expression from the selected target genes with transcriptional activity. (c) The expression levels of the top five miRNAs (miR-146a-5p, miR-125a-5p, miR-34a-5p, miR-29b-3p, and miR-21-5p) in sepsis model were detected by RT-qPCR. ∗∗∗P < 0.001 vs. the control group.