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. 2021 Oct 15;2021:1530445. doi: 10.1155/2021/1530445

Figure 6.

Figure 6

Effects of miR-146a-5p overexpression on LPS-induced sepsis model in vitro. The NC mimics and miR-146a-5p mimics were transfected into the LPS-induced H9C2 cells. (a) The expression level of miR-146a-5p in LPS-induced H9C2 cells was examined by RT-qPCR. ∗∗∗P < 0.001 vs. the control group. (b) The cell viability was detected by CCK-8 assay. (c) The cell proliferation was measured by EdU assay. (d) The cell apoptosis was assessed by flow cytometry assay. (e) The protein levels of caspase-3, cleaved-caspase-3, caspase-9, and cleaved-caspase-9 were detected by Western blot assay. ∗P < 0.05, ∗∗∗P < 0.001, #P < 0.05, ###P < 0.001 vs. the LPS group.