Figure 8.

MiR-146a-5p inhibited the sepsis induced by LPS treatment through regulating MYBL1 in vitro. The pcDNA-MYBL1 and pcDNA-NC were transfected into LPS-induced H9C2 cells treated with miR-146a-5p mimics. (a) The cell viability was detected by CCK-8 assay. (b) The cell proliferation was examined by EdU assay. (c) The cell apoptosis was assessed by flow cytometry assay. (d) The protein levels of caspase-3, cleaved-caspase-3, caspase-9, and cleaved-caspase-9 were detected by Western blot assay. ^∗∗∗P < 0.001, ^#P < 0.05, ^##P < 0.01 vs. the NC mimics + pcDNA-NC.