Table 1.
Immunological profile of the index patient at day 8 after initial symptoms of COVID-19
| Test | Result | Normal range for age |
|---|---|---|
| White blood cells (10^3/µL) | 5.8 | 4–11 |
| Platelets (10^3/µL) | 74↓ | 150–450 |
| Neutrophil (%) | 70↑ | 20–45 |
| Lymphocyte (%) | 22↓ | 46–76 |
| CD3+ T cells (%) | 80↑ | 30–78 |
| CD4+ helper T cells (%) | 35 | 22–58 |
| CD4+ CD45RA+ CCR7+ naïve helper T cells (%) | 3.9↓ | 11–53 |
| CD4+ CD45RA− CCR7+ central memory helper T cells (%) | 15 | 10–32 |
| CD4+ CD45RA− CCR7− effector memory helper T cells (%) | 65↑ | 0–40 |
| CD4+ CD45RA+ CCR7− TEMRA helper T cells (%) | 6.1 | 5–15 |
| CD4+ CD25+ FOXP3+ CD127−/low regulatory T cells (%) | 5.5 | 5–10 |
| CD8+ cytotoxic T cells (%) | 40↑ | 10–37 |
| CD8+ CD45RA+ CCR7+ naïve cytotoxic T cells (%) | 26 | 25–70 |
| CD8+ CD45RA− CCR7+ central memory cytotoxic T cells (%) | 11↑ | 2–7 |
| CD8+, CD45RA− CCR7− effector memory cytotoxic T cells (%) | 43 | 15–60 |
| CD8+, CD45RA+ CCR7− TEMRA cytotoxic T cells (%) | 51↑ | 5–45 |
| CD19+ B cells (%) | 3.0*↓ | 6–14 |
| Red blood cells (10^6/µL) | 3.27↓ | 4.2–6.3 |
| Hemoglobin (g/dl) | 7.9↓ | 12–16 |
| Hematocrit (%) | 22.6↓ | 30–45 |
| Mean corpuscular volume (fl) | 69.1↓ | 80–100 |
| Mean corpuscular hemoglobin (pg) | 24.2↓ | 27–32 |
| Mean corpuscular hemoglobin concentration (g/dl) | 35.0 | 33–38 |
| ESR 1 h (mm/h) | 140↑ | < 50 |
| HIV DNA PCR | Negative | Negative |
| HIV antibody | 0.3 | < 1 |
| 50% hemolytic complement (CH50, U/ml) | 8.8↓ | 50–150 |
| Nitro blue tetrazolium test (%) | 98 | 90–100 |
| Alpha fetoprotein (ng/ml) | 67↑ | > 20 |
*B cell subset was not reliable in this patient due to low absolute count of B cells