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. 2021 Oct 23;59(1):106462. doi: 10.1016/j.ijantimicag.2021.106462

Figure 1.

Figure 1

Flowchart of patient enrolment. Patients with non-severe coronavirus disease 2019 (COVID-19) include mild cases and moderate cases. Patients with severe COVID-19 include severe cases and critical cases. Patients with the following two conditions were designated as bacterial infections in this study: (i) patients with positive microbiological cultures, including blood, sputum, urine, stool and tracheal secretions; and (ii) patients with no evidence of positive microbiological cultures, but in whom the clinical picture radiological evidence laboratory tests strongly suggest bacterial infection. NEAU, non-early antibiotic use; EAU, early antibiotic use.