Figure 5.

AP205-RBD induced durable humoral memory

(A and B) Splenocytes or bone marrow (BM) cells from mice immunized with AP205-RBD twice 3–4 months previously were examined for anti-RBD IgG-secreting cells by ELISpot assay. Representative data are shown in (A), and quantification data are shown in (B). Symbols indicate data collected from individual mice, and bars indicate the geometric mean of each group.

(C) Anti-RBD IgG in mice immunized with AP205-RBD was examined for up to 1 year after immunization. The geometric mean and standard deviation for each time point are shown. There are six to eight individuals for each time point, except for the last time point there are four individuals.

See also Figure S5.