Table 1.

Significant results from the main-effect analyses of previously implicated SNPs in relation to lifetime tic severity

SNP	Position	Chromosome	Gene	Category	Main effect in initial sample		Replication main effect
					F	Pa	F	Pa
rs7123010	86,341,186	11	ME3	GWAS TS	7.99	0.0004*	1.98	0.14

SNP single-nucleotide polymorphism, GWAS genome-wide association study, TS Tourette syndrome

*Significant after correcting for multiple testing (P_all = 0.0014)

^aAnalyses were corrected for age, sex, and socioeconomic status