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Steady state Ruxolitinib trough serum concentrations of all samples across all individuals
| Daily dose (mg) | No. of samples (no. of excluded samples < LLOQ) | Median (ng/mL) | IQR (ng/mL) | Range (ng/mL) |
|---|---|---|---|---|
| All | 174 (8) | 31.4 | 31.95 | 2.2–229 |
| 20 | 120 (2) | 40.5 | 33.9 | 2.7–229 |
| > 20–40 | 3 (1) | 25.1 | 12.1 | 4.3–28.5 |
| 5–< 20 | 51 (5)a | 17.5 | 10.9 | 2.2–155 |
LLOQ lower limit of quantification (2 ng/mL)
aAll trough serum concentrations at 5 mg daily were ≤ 2.17 ng/mL (3 of 4 samples < LLOQ)
