Table 1.
Data for Fig. 1: 40-year-old male, 68 inches tall, 160 lbs
| Drinking variables | Pre-consumption | Consumption 1 | Consumption 2 | Consumption 3 | Consumption 4 |
|---|---|---|---|---|---|
| % alcohol of drink | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 |
| Fluid ounces per drink | 1.5 | 1.5 | 1.5 | 1.5 | 1.5 |
| Number of drinks | 0 | 3 | 2 | 2 | 2 |
| Time (hr) since last drink | 0 | 1 | 1 | 1 | 1 |
| Grams alcohol | 0 | 42.04854 | 28.03236 | 28.03236 | 28.03236 |
| BAC first-order elimination | 0.000000 | 0.080881 | 0.078801 | 0.076721 | 0.074642 |
| BAC high zero-order eliminiation | 0.000000 | 0.080881 | 0.114801 | 0.148721 | 0.182642 |
| Chemical and physiological parameters | |
|---|---|
| 29.57 | mls. per fluid ounce |
| 0.79 | Specific. Gravity Ethanol |
| 72.576 | Body weight in kg |
| 172.72 | Height in cm |
| 0.01 | Slow zero-order elimination rate (g%/h) |
| 0.02 | High zero-order elimination rate (g%/h) |
| 0.056 | First-order elimination rate (g%/h) at 0.08 g% |
| Calculated quantities | |
|---|---|
| Water content of blood (B) | 0.8 |
| TBW (Liters) | 41.5907792 |
| TBW (Deciliters) | 415.907792 |
| B/TBW Quotient | 0.001923503 |
Blood alcohol concentrations (BAC) resulting from consumption of three standard alcoholic beverages (Consumption 1) followed by 2 alcoholic beverages every hour for 3 consecutive hours (Consumption 2, 3, 4) assuming either first-order or zero-order elimination kinetics
BACs were calculated by the Total Body Water (TBW) method of Watson et al. (1981) using the following formula:
Male Total Body Water (TBW) Volume [70.4% confidence interval (Watson et al. 1980)] = 2.447–0.09516 (age in yrs) + 0.1074 (height in cm) + 0.3362 (weight in kg). Underlined values are independent (entered) variables; values not underlined are dependent (calculated) variables
A zero-order alcohol elimination rate of 0.2 g percent per hour was assumed, which represents a rate near the high end of the normal range for non-alcoholic adults (Jones 2010; Norberg et al. 2003). A first-order alcohol elimination rate of 0.056 g percent per hour was interpolated from the data found in Fig. 2 of the publication by Høiseth et al. (2016)
The alcohol content of a standard alcoholic beverage consisting of 1.5 oz of 80 proof (40%) ethanol was calculated as follows: (#drinks) (ounces per drink) (% alcohol) (29.57 ml per fl. oz.) (0.79 g alcohol per milliliter) = grams alcohol total