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. 2021 Oct 22;11:20928. doi: 10.1038/s41598-021-00472-7

Table 2.

Prevalence of psychiatric comorbidity of total, men, and women with CUD (DSM-IV-TR).

Variable Cocaine use disorder
Total N = 272 Men N = 228 Women N = 44 p Value
Mood disorders

Major depressive disorder

[N (%)]

Yes

No

73 (26.80)

198 (72.80)

61 (26.80)

166 (72.80)

12 (27.30)

32 (72.70)

 < 0.999

Dysthymia

[N (%)]

Yes

No

10 (3.70)

261 (96)

8 (3.50)

219 (96.10)

2 (4.50)

42 (95.50)

0.667

Manic episode

[N (%)]

Yes

No

5 (1.80)

265 (97.40)

5 (2.20)

221 (96.90)

44 (100)

 < 0.999

Hypomanic episode

[N (%)]

Yes

No

4 (1.50)

268 (98.50)

3 (1.30)

225 (98.70)

1 (2.30)

225 (98.70)

0.508

Cyclothymia

[N (%)]

Yes

No

4 (1.50)

266 (97.80)

2 (0.90)

224 (98.20)

2 (4.50)

42 (95.5)

0.126
Anxiety disorders

Generalized anxiety disorder

[N (%)]

Yes

No

29 (10.70)

241 (88.60)

19 (8.30)

207 (90.80)

10 (22.70)

34 (77.30)

0.013

Obsessive compulsive disorder

[N (%)]

Yes

No

3 (1.10)

267 (98.20)

2 (0.90)

224 (98.20)

1 (2.30)

43 (97.70)

0.415

Post traumatic stress disorder

[N (%)]

Yes

No

24 (8.90)

247 (90.80)

13 (5.70)

214 (93.90)

11 (25.00)

33 (75.00)

 < 0.001

Panic attack

[N (%)]

Yes

No

11 (4)

260 (95.60)

8 (3.50)

219 (96.10)

3 (6.80)

41 (93.20)

0.257

Specific phobias

[N (%)]

Yes

No

8 (2.90)

263 (96.70)

5 82.20)

222 (97.40)

3 (6.80)

41 (93.20)

0.124

Social phobias

[N (%)]

Yes

No

1 (0.40)

271 (99.60)

1 (0.40)

227 (99.60)

44 (100.00)

 < 0.999
Psychotic disorders

Schizophrenia

[N (%)]

Yes

No

272 (100)

228 (100)

44 (100)

Schizophreniform disorder

[N (%)]

Yes

No

3 (1.10)

269 (98.90)

2 (0.90)

226 (99.10)

1 (2.30)

43 (97.70)

0.412

Delusional disorder

[N (%)]

Yes

No

4 (1.50)

268 (98.5)

3 (1.30)

225 (98.70)

1 (2.30)

43 (97.70)

0.508

Schizoaffective disorder

[N (%)]

Yes

No

3 (1.10)

269 (98.90)

2 (0.90)

226 (99.10)

1 (2.30)

43 (97.70)

0.412

Unspecified psychotic disorder

[N (%)]

Yes

No

5 (1.80)

267 /98.20)

4 (1.80)

224 (98.2)

1 (2.30)

43 (97.70)

0.589

Brief Psychotic Disorder

[N (%)]

Yes

No

14 (5.10)

258 (94.90)

13 (5.70)

215 (94.30)

1 (2.30)

43 (97.70)

0.703
Eating disorders

Anorexia

[N (%)]

Yes

No

4 (1.50)

267 (98.20)

228 (100)

4 (9.10)

40 (90.90)

0.001

Bulimia

[N (%)]

Yes

No

7 (2.60)

264 (97.10)

4 (1.80)

223 (97.80)

3 (6.80)

41 (93.20)

0.021
Personality disorders

Antisocial personality disorder

[N (%)]

Yes

No

60 (22.10)

210 (77. 20)

53 (23.50)

173 (76.50)

7 (15.90)

37 (84.10)

0.325

Borderline personality disorder

[N (%)]

Yes

No

52 (19.10)

218 (80.10)

41 (18)

185 (81.10)

11 (25)

33 (75)

0.300
Other substance use disorders

Alcohol use disorder

[N (%)]

Yes

No

154 (56.60)

118 (43.40)

138 (60.50)

90 (39.50)

16 (36.40)

28 (63.60)

0.004

Cannabis use disorder

[N (%)]

Yes

No

68 (25.10)

203 (74.90)

64 (28.20)

163 (71.80)

5 (11.40)

39 (88.60)

0.022

Sedative use disorder

[N (%)]

Yes

No

28 (10.30)

244 (89.70)

24 (10.50)

204 (89.50)

4 (9.10)

40 (90.90)

0.999

N number of patients, % percentage.

P-value of the Chi-Square test. Significant P-value in bold.