Table 3.
Proteins with different levels in the peritoneal fluid from endometriosis patients versus control patients.
| Protein | Protein abbreviation | logFC | adjustedp-value* | Uniprot identifier |
|---|---|---|---|---|
| Angiotensinogen | AGT, ANGT | 1.70 | 3.1e−03 | P01019 |
| Proinflammatory calcium binding protein S100A8/9 | S10A8/9 | 1.66 | 2.8e−04 | P05109 |
| Scavenger receptor cysteine-rich type 1 protein M130 | C163A | 1.43 | 5.2e−07 | Q86VB7 |
| Transforming growth factor-β-induced protein ig-h3 | TGFBI, BGH3 | 1.23 | 3.8e−03 | Q15582 |
| Epidermal growth factor receptor | EGFR, HER1 | 1.13 | 1.1e−02 | P00533 |
| Tissue inhibitor of metalloproteinase 1 | TIMP1 | 1.08 | 2.8e−04 | P01033 |
| Lumican | LUM | 0.95 | 1.3e−03 | P51884 |
| Cartilage oligomeric matrix protein/thrombospondin 5 | COMP | 0.84 | 6.3e−04 | P49747 |
| α-2-Antiplasmin | A2AP, SERPINF2 | 0.77 | 4.8e−02 | P08697 |
| Phospholipid hydroperoxide glutathione peroxidase | GPX4 | 0.72 | 3.2e−02 | P36969 |
| Insulin-like growth factor-binding protein 4 | IBP4, IGFBP4 | 0.68 | 4.8e−02 | P22692 |
| Hepatocyte growth factor activator | HGFA | 0.68 | 3.2e−02 | Q04756 |
| Matrix metalloproteinase-2 | MMP2 | 0.66 | 8.2e−03 | P08253 |
| Dickkopf-related protein 3 | DKK3 | 0.60 | 2.7e−03 | Q9UBP4 |
| Cellular tumour antigen p53 | P53 | 0.59 | 1.1e−02 | P04637 |
| Angiopoietin-4 | ANGP4 | 0.53 | 4.7e−02 | Q9Y264 |
The proteins given in bold were selected for the validation study.
*p values adjusted for multiple testing according to Bonferoni and Hochberg.