Table 2.

Association of WT/Ins-I148M haplotype with NAFLD. WT-148I haplotype is protective, while WT-148M increases the risk of NAFLD. Both effects are attributable to the I148M variant itself, with no contribution of the WT/Ins variant. Number of subjects (haplotype frequencies) are shown. Results are expressed as OR [5–95%].

	WT-148I	WT-148M	Ins-148I	Ins-148M
NAFLD	62 (0.254)	88 (0.361)	94 (0.385)	0
Control	111 (0.332)	85 (0.254)	138 (0.413)	0
OR [95% CI]	0.68 [0.47–0.99]	1.65 [1.15–2.37]	0.89 [0.64–1.25]	na
	p = 0.043	p = 0.006	p = 0.499	na
	Global p = 0.026