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Combination treatment with palbociclib and ganetespib inhibits tumor growth in vivo . (A) Tumors excised from HT29 xenografts in nude mice. (B) Tumor weight quantification of excised tumors. (C) Tumor volume measured over time. (D) Body weight of mice in different treatment groups. (E) Combination treatment inhibits microvessel formation in tumors in vivo. Statistical analysis was performed using unpaired two-tailed t test. Mean ± SD was shown. *p < 0.05, **p < 0.01.
