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. 2021 Apr 15;144(9):2594–2609. doi: 10.1093/brain/awab155

Figure 7.

Figure 7

Viral therapy in pHGG. A tumour cell-specific virus is injected into the tumour bulk or resection cavity. A pro-drug such as ganciclovir is then administered and subsequently converted by the virus to a cytotoxic agent, which kills tumour cells and induces and amplifies an active immune response.