Table 1.
Feature | Number of Compounds Fulfilling the Rule | Percentage of Curated Database Fulfilling the Rule |
---|---|---|
Molecular weight | 8691 | 92.07% |
LogP | 8190 | 86.76% |
H-bond acceptors | 9356 | 99.11% |
H-bond donors | 9403 | 99.61% |
Complete Lipinski’s rules | 7735 | 81.94% |
Polar Surface Area | 9382 | 99.39% |
Rotatable Bonds | 8848 | 93.73% |
Complete Veber et al.’s rules | 7431 | 78.72% |