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. 2021 Oct 16;13(10):1711. doi: 10.3390/pharmaceutics13101711

Table 1.

Summary of compounds from the curated database fulfilling the rule of five.

Feature Number of Compounds Fulfilling the Rule Percentage of Curated Database Fulfilling the Rule
Molecular weight 8691 92.07%
LogP 8190 86.76%
H-bond acceptors 9356 99.11%
H-bond donors 9403 99.61%
Complete Lipinski’s rules 7735 81.94%
Polar Surface Area 9382 99.39%
Rotatable Bonds 8848 93.73%
Complete Veber et al.’s rules 7431 78.72%