Table 2.
Examples of approved drugs present in the curated database.
| No. | Drug | pKi | The Rule of Five |
|---|---|---|---|
| 1. | Amoxapine | 6.66 | ✓ |
| 2. | Apomorphine | 6.53 | ✓ |
| 3. | Aripiprazole | 8.77 | ✓ |
| 4. | Bromocriptine | 7.62 | MW over limit |
| 5. | Buspirone | 7.46 | ✓ |
| 6. | Cariprazine | 8.59 | ✓ |
| 7. | Clozapine | 6.80 | ✓ |
| 8. | Haloperidol | 5.77 | ✓ |
| 9. | Lisuride | 9.40 | ✓ |
| 10. | Lofexidine | 6.90 | ✓ |
| 11. | Naluzotan | 8.29 | ✓ |
| 12. | Olanzapine | 5.57 | ✓ |
| 13. | Pergolide | 8.40 | ✓ |
| 14. | Pindolol | 7.65 | ✓ |
| 15. | Quetiapine | 6.52 | ✓ |
| 16. | Risperidone | 6.72 | ✓ |
| 17. | Sumatriptan | 6.64 | ✓ |
| 18. | Vilazodone | 9.70 | ✓ |
| 19. | Vortioxetine | 8.02 | ✓ |
| 20. | Ziprasidone | 8.70 | ✓ |