TABLE 1.
Percents agreement between endpoints for voriconazole and fluconazolea
| Endpoints compared | % Agreement for the following drug at the indicated time
|
|||
|---|---|---|---|---|
| Voriconazole
|
Fluconazole
|
|||
| 24 h | 48 h | 24 h | 48 h | |
| BA-1 vs AA-1 | 90 | 94 | 83 | 95 |
| BA-2 vs AA-2 | 97 | 88 | 94 | 96 |
| AA-1 vs Spec-50 | 91 | 86 | 92 | 85 |
| AA-1 vs Spec-80 | 96 | 94 | 95 | 97 |
| AA-2 vs Spec-50 | 99 | 95 | 99 | 91 |
| AA-2 vs Spec-80 | 96 | 90 | 97 | 87 |
a
Testing was performed in RPMI 1640–2%, and the paired readings on the 209 isolates were said to be in agreement if they were within 1 dilution of each other. The microtiter plates were visually read before and after agitation. Spectrophotometric readings were made after agitation of the plates. Spec-80 and Spec-50 corresponded to the lowest drug concentrations reducing control growth by 80 and 50%, respectively.