Table 2.
Data for NAT yield samples with substitutions in amino acids 100-160 of the HBsAg S protein.
| Sample | Anti-HBs | HBsAgNx | Genotype | S Protein Amino Acid Substitutions |
|---|---|---|---|---|
| SANBS83 | − | − | A1 | T143M |
| 254 | − | − | C2 | Q101H, R160S |
| AM8.98000 | − | − | B4 | T131N |
| BM7.00531 | − | − | B4 | P127T |
| BM6.33816 | − | − | C1 | Y100C |
| 264 | − | + | E | I110IL |
| 97 | − | + | A2 | Y100S |
| 291 | − | + | A1 | A159G |
| 292 | − | + | C5 | L110I, R160K |
| AM9.92991 | − | + | B4 | A128V |
| BM9.02298 | − | + | B4 | I110L, T143M |
| BM3.32643 | − | + | B4 | I110L, S113T |
| 300 | + | − | H | S143T |
Anti-HBs values ≥10 mIU/mL are shown as positive(+). Anti-HBs values <10 mIU/mL are shown as negative(−). HBsAg NEXT assay results are indicated as negative(−) or positive(+).