Table 1.
Performance of deterioration risk scores in COVID-19 patients.
First Author | Triaging Test | Population/Study Type | Outcome | Discriminatory Performance (ROC AUC) |
---|---|---|---|---|
Beals et al. [13] | Rothman index | 3499 COVID-19 patients (retrospective, multicenter study) | Identification of patients at admission with high risk for subsequent deterioration | 0.81–0.84 |
Su et al. [14] | CRB-65, qSOFA | 116 COVID-19 patients (retrospective single center study) | Identification of patients who require intensive respiratory or vasopressor support | 0.81 ± 0.05 for CRB-65 0.70 ± 0.06 for qSOFA |
Volff et al. [15] | NEWS, mNEWS | 363 COVID-19 patients (retrospective single center study) | Identification of patients at risk for clinical deterioration (ICU admission or death) | 0.74 for NEWS 0.72 for mNEWS |
Guo et al. [16] | CURB-65 | 74 COVID-19 patients (retrospective single center study) | Identification of patients at risk for in-hospital death | 0.81 |
Hu et al. [17] | MEWS, REMS | 105 COVID-19 patients (retrospective single center study) | Identification of patients at risk for in-hospital death | 0.677 for MEWS 0.833 for REMS |
Ucan et al. [18] | PSI, CURB-65 A-DROP | 298 patients with probable or definitive COVID-19 (retrospective single center study) | Identification of patients at risk for in-hospital death and progression to severe disease | PSI: 0.873 for overall mortality & 0.697 for progression to severe COVID-19 CURB-65: 0.859 for overall mortality & 0.739 for progression to severe COVID-19 A-DROP: 0.875 for overall mortality & 0.660 for progression to severe COVID-19 |
ROC AUC: Area Under the Receiver Operating Characteristic Curve, qSOFA: quick Sequential Organ Failure Assessment, NEWS: National Early Warning Score, mNEWS: modified National Early Warning Score, MEWS: Modified Early Warning Score, REMS: Rapid Emergency Medicine Score, PSI: pneumonia severity index.