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. 2021 Sep 27;11(10):961. doi: 10.3390/jpm11100961

Table 1.

Performance of deterioration risk scores in COVID-19 patients.

First Author Triaging Test Population/Study Type Outcome Discriminatory Performance (ROC AUC)
Beals et al. [13] Rothman index 3499 COVID-19 patients (retrospective, multicenter study) Identification of patients at admission with high risk for subsequent deterioration 0.81–0.84
Su et al. [14] CRB-65, qSOFA 116 COVID-19 patients (retrospective single center study) Identification of patients who require intensive respiratory or vasopressor support 0.81 ± 0.05 for CRB-65
0.70 ± 0.06 for qSOFA
Volff et al. [15] NEWS, mNEWS 363 COVID-19 patients (retrospective single center study) Identification of patients at risk for clinical deterioration (ICU admission or death) 0.74 for NEWS
0.72 for mNEWS
Guo et al. [16] CURB-65 74 COVID-19 patients (retrospective single center study) Identification of patients at risk for in-hospital death 0.81
Hu et al. [17] MEWS, REMS 105 COVID-19 patients (retrospective single center study) Identification of patients at risk for in-hospital death 0.677 for MEWS
0.833 for REMS
Ucan et al. [18] PSI, CURB-65 A-DROP 298 patients with probable or definitive COVID-19 (retrospective single center study) Identification of patients at risk for in-hospital death and progression to severe disease PSI: 0.873 for overall mortality & 0.697 for progression to severe COVID-19
CURB-65: 0.859 for overall mortality & 0.739 for progression to severe COVID-19
A-DROP: 0.875 for overall mortality & 0.660 for progression to severe COVID-19

ROC AUC: Area Under the Receiver Operating Characteristic Curve, qSOFA: quick Sequential Organ Failure Assessment, NEWS: National Early Warning Score, mNEWS: modified National Early Warning Score, MEWS: Modified Early Warning Score, REMS: Rapid Emergency Medicine Score, PSI: pneumonia severity index.