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. 2021 Oct 13;22(20):11055. doi: 10.3390/ijms222011055
1-M-d-T 1-Methyl-D-tryptophan
3-HANA 3-hydroxyanthranilic acid
3-HAOO 3-hydroxyanthranilic oxidase
3-HK-3 hydroxykinurenine
AA anthranilic acid
AhR aryl hydrocarbon receptor
AMPA α-amino-2,3-dihydro-5-methyl-3-oxo-isoxazolpropionic acid
APCs antigen-presenting cells
BBB blood–brain barrier
BH4 tetrahydrobiopterin
C1q complement component 1q
CCI chronic constriction injury
CD40 cluster of differentiation 40
CNS central nervous system
DCs dendritic cells
DRG dorsal root ganglia
GFAP glial fibrillary acidic protein
GPR35 G-protein coupled receptor 35
HCN channels hyperpolarization-activated cyclic nucleotide–gated channels
HIV human immunodeficiency virus
IASP The International Association for the Study of Pain
IBA-1 allograft inflammatory factor 1
IDO indoleamine 2,3-dioxygenase
IFN-1β interferon beta -1
IFN-6 interferon-6
IFN-gamma interferon gamma
IL-1 interleukin 1
IL-10 interleukin-10
IL-1β interleukin 1 beta
IL-4 interleukin-4
IL-6 interleukin-6
KAR kainic acid receptor
KATs kynurenine aminotransferases
KM Michaelis constant
KMO kynurenine-3-monooxygenase
KP kynurenine pathway
KYNA kynureinc acid
KYNU kynureninase
L-KYN L-kynurenine
L-KYN L-kynurenine
MAO-B B monoamine oxidase
NAD nicotinamide adenine dinucleotide
NMDA N-methyl-D-aspartate
NOS2 Nitric oxide synthase 2
QUIN quinolinic acid
ROS reactive oxygen species
SC spinal cord
SNI sciatic nerve injury
SNL spinal nerve ligation
SNRIs serotonin-noradrenaline reuptake inhibitors
SOD superoxide dismutase
TCAs tricyclic antidepressants
TDO tryptophan 2,3-dioxygenase
TNF-α tumor necrosis alpha
TRP tryptophan
UPF648 (1S,2S)-2-(3,4-Dichlorobenzoyl)cyclopropanecarboxylic acid
XA xanturenic acid