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. 2021 Oct 18;22(20):11211. doi: 10.3390/ijms222011211

Figure 8.

Figure 8

Analysis of cytokines in SputnikV vaccinated and convalescent COVID-19 sera. A and B Serum samples before (D0), after vaccination on D21 and D42 (21 and 42 days after the first dose of vaccine, respectively) as well as 42.0 ± 11.1 days (median ± SEM) after COVID-19 convalescence were used to analyze 48 cytokines (Bio-Plex Pro Human Cytokine 48-plex Screening Panel (12007283, BioRad, Hercules, USA)). Each sample was tested in triplicate. Data were analyzed with MasterPlex CT control software and MasterPlex QT analysis software (MiraiBio, San Bruno, CA, USA). Data are presented as a Log2 difference between a vaccinated or convalescent sample and controls. Cytokines IL-1β, IL-18, CCL27, CXCL1 and VEGF did not differ significantly and were not included in the figure *—Significant difference between D21 and D0; *—significant difference between D42 and D0; *—significant difference between COVID-19 convalescent and D0.