Table 3.
Metabolic pathways identified from the significantly differentially abundant metabolites (SDMs) between termites fed M. micrantha leaves (ML) and pinewood (PW) diets.
| Pathway | −log10(p) | Impact | SDMs 1 |
|---|---|---|---|
| Glycine, serine and threonine metabolism | 4.2426 | 0.2793 | 1,3-diaminopropane↑, Pyruvate↑, Serine↑, Glycocyamine↓ |
| Tryptophan metabolism | 2.7729 | 0.2645 | 5-Hydroxy-l-tryptophan↓, l-Kynurenine↓ |
| Starch and sucrose metabolism | 5.8532 | 0.2516 | Glucose-1-phosphate↑, Isomaltose↑, Maltose↓ |
| Galactose metabolism | 3.8386 | 0.2514 | Glucose-1-phosphate↑, Lactose↑, Melibiose↑, myo-Inositol↑, N-Acetyl-d-galactosamine↑, Sorbitol↑, Tagatose↓ |
| Sphingolipid metabolism | 3.4365 | 0.2146 | Serine↑, Sphinganine↓ |
| Pyruvate metabolism | 3.7194 | 0.1654 | Pyruvate↑ |
| Pyrimidine metabolism | 2.8521 | 0.1417 | Uridine↑, Thymine↓, UMP↓ |
| Amino sugar and nucleotide sugar metabolism | 1.8373 | 0.1147 | Glucose-1-phosphate↑ |
| Citrate cycle (TCA cycle) | 6.5818 | 0.1049 | Pyruvate↑, 2-Oxoglutarate↓ |
| Glycolysis/Gluconeogenesis | 3.0713 | 0.0991 | Glucose-1-phosphate↑, Pyruvate↑ |
| Lysine degradation | 2.24 | 0.069 | Saccharopine↑, 5-Aminovaleric acid↓ |
| Alanine, aspartate and glutamate metabolism | 6.5818 | 0.0676 | Pyruvate↑, 2-Oxoglutarate↓ |
| Fructose and mannose metabolism | 1.5513 | 0.0459 | Sorbitol↑ |
| Fatty acid biosynthesis | 3.4695 | 0.0168 | Palmitic acid↑ |
| Purine metabolism | 2.9125 | 0.0025 | dAMP↓ |
| Tyrosine metabolism | 5.2416 | 0 | 4-Hydroxyphenylacetic acid↑, Pyruvate↑, Tyrosine↓ |
| Cysteine and methionine metabolism | 4.2426 | 0 | Pyruvate↑, Serine↑ |
| d-Glutamine and d-glutamate metabolism | 3.9902 | 0 | Glutamic acid↑, 2-Oxoglutarate↓ |
| Butanoate metabolism | 3.8176 | 0 | 3-Hydroxybutyric acid↑, 2-Oxoglutarate↓ |
| Fatty acid elongation | 3.4695 | 0 | Palmitic acid↑ |
| Pentose and glucuronate interconversions | 2.2258 | 0 | d-Arabitol↑, Glucose-1-phosphate↑ |
| Pentose phosphate pathway | 1.8912 | 0 | Ribose↑ |
1 ↑ and ↓ indicate that the metabolites were upregulated and downregulated in termites fed an ML diet relative to those fed a PW diet, respectively.