Table 4.

Theoretical affinity of selected ligands to tel₂₆ and c-myc G4 structures calculated along MD trajectories.

Compound	tel26 (MM-GBSA) kcal/mol ± SEM	c-myc (MM-GBSA) kcal/mol ± SEM
Bulbocapnine	−16.85 ± 0.43	−38.57 ± 0.35
Chelidonine	−17.49 ± 0.31	−25.07 ± 0.42
Ibogaine	−23.92 ± 0.34	−21.56 ± 0.71
Rotenone	−4.47 ± 0.73	−9.47 ± 0.42
Vomicine	−20.52 ± 0.33	−12.81 ± 0.49