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. 2021 Oct 7;10(10):1291. doi: 10.3390/pathogens10101291

Figure 2.

Figure 2

Virus-specific antibody responses were detected from the sera of mice (n = 6) 4 weeks after immunization. IgG (A), IgG1 (B), and IgG2a (C) responses were confirmed by ELISA. Data are presented as median ± SD (* p < 0.05, ** p < 0.01, *** p < 0.001) and are representative of the three independent experiments performed in triplicates. Abbreviations: HA VLPs—virus-like particles (VLPs) expressing hemagglutinin (HA) antigen only; NA VLPs—VLPs expressing neuraminidase (NA) antigen only; HANA VLPs—VLPs expressing both HA and NA antigens; M1 VLPs—VLPs expressing only M1 antigen.