Table 1.

Pathway analysis using Gene Set Enrichment Analysis (GSEA) of genes expressed in five aldosterone-producing adenomas (APA) with an ATP1A1 mutation and five non-functioning adrenocortical adenomas (NFA).

Ranking	Pathway Increased in APA with ATP1A1 Mutation
1	Cancer Head and Neck vs. Cervical Down
2	Ion Transport by P Type ATPase
3	Proximal Tubule Bicarbonate Reclamation
4	Kidney
5	LG1 Targets Up

The transcriptome data from microarray analysis were analyzed by the R software package. The pathways highly expressed in ATP1A1 mutated APA in contrast to NFA were detected.