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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
A simplified view of T cell activation. Inputs are different methods of stimulation and their respective targets. Outputs are expressed proteins and molecules targeting other immune cells. 1 = PKC/NF-kB pathway. 2 = Ras/AP-1 pathway. 3 = Calcineurin/NFAT pathway.