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. 2021 Oct 13;13(10):3576. doi: 10.3390/nu13103576

Figure 5.

Figure 5

The effect of the experimental diets (ketogenic diet, KD; low methyl ketogenic diet, LMKD; and control) on the vascular content of specific epigenetic tags at lysine 27 on histone H3 (H2K27me3, tri-methylation; H3K27ac, acetylation) in the aortic arch and brachiocephalic artery (BCA). (A) Representative images of brightfield and immunofluorescence quantification of BCA cross sections. Total histone 3 (H3) in green, and histone 3 trimethylation at lysine 27 (H3K27me3) or acetylation (H3K27ac) in magenta. Scale bars = 200 μm. (B) Immunohistochemistry results. Data are the mean ± SD, n = 35. Bars bearing different letters were significantly different (p < 0.05).