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. 2021 Oct 2;13(10):1981. doi: 10.3390/v13101981

Figure 5.

Figure 5

Compounds binding precursors of viral proteases: efavirenz binds to the Gag-Pol precursor, leading to the premature activation of the HIV protease, whereas ARDP0006 and the carbazole derivative SP-471 block intrahelicase cis-cleavage in Dengue NS3.