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. 2021 Oct 12;22(20):11012. doi: 10.3390/ijms222011012

Figure 1.

Figure 1

BZA promotes survival of PC12 neural cells and reduces in vitro NO production. Cell viability was significantly higher in LPS + BZA-treated cells compared with LPS-treated cells. NO production significantly decreased in response to 10 μM and 20 μM BZA treatment compared with LPS-treated cells. (A) Quantitative bar graph illustrating the percentage of live PC12 neural cells according to treatment group at 24 h following culture. (B) Quantitative bar graph illustrating inhibition of NO production in LPS-stimulated RAW264.7 cells treated with BZA. Standard curves to confirm the correlation between NO concentration and absorbance were obtained in two ways: (C) 9 serial 2-fold dilutions and (D) 6 serial 2-fold dilutions. Data are presented as mean ± SEM (n = 3 (B–D), n = 7 (A); performed in triplicate). *** p < 0.001 (LPS-treated vs. control, DMSO), ## p < 0.01, ### p < 0.001 (LPS-treated vs. LPS + BZA 10 μM), $$$ p < 0.001 (LPS-treated vs. LPS + BZA 20 μM), one-way ANOVA followed by the Bonferroni test.