Skip to main content
. 2021 Oct 12;22(20):11012. doi: 10.3390/ijms222011012

Figure 2.

Figure 2

BZA promotes the resolution of inflammation in vitro. Total RNA was extracted from the LPS- and BZA (10 μM and 20 μM)-treated RAW 264.7 cells at 24 h following incubation (n = 3, performed in triplicate). The mRNA levels of proinflammatory cytokines including IL-6 (A), TNF-α (B), and CCL2 (C) and an anti-inflammatory cytokine, IL-10 (D), were measured. For time, 18 s was used as internal control for qRT-PCR. Data represent mean ± SEM (n = 3 (A,C), n = 4 (D), n = 6 (B); performed in triplicate). *** p< 0.001 (LPS-treated vs. control, DMSO), ## p < 0.01, ### p < 0.001 (LPS-treated vs. LPS + BZA 10 μM), $$$ p < 0.001 (LPS-treated vs. LPS + BZA 20 μM), NS = Not significant, one-way ANOVA followed by the Bonferroni test.