Figure 5.

Electrophysiological classification of neural changes after chondroitinase or penicillinase treated animals as determined by extracellular recording of spontaneous neuronal activity in the PFC. (A) example firing patterns of spontaneously recorded neurons in different groups; (B) characteristic frequency for bursting, tonic, and irregularly firing neurons; (C–E) percent distribution of types pf neurons as recorded spontaneously from PFC of animals, i.e. fast spiking, tonic and irregularly firing neurons respectively. The data are shown as mean ± s.e.m. where * or # p ≤ 0.05, ## p ≤ 0.01, where the symbols express the comparison of chDISC1 mutation animals with * represents comparison vs. penicillinase control and # represents comparison vs. chondroitinase control.