Figure 3.

VV-GMCSF-Lact biodistribution in SCID mice with orthotopic transplanted U87 MG tumors and in healthy SCID mice. Tissues were collected from mice administered with VV-GMCSF-Lact. The amount of the virus was determined by a real-time PCR assay using standard VV-GMCSF-Lact dilutions. The data represent the mean ± SD of five mice for a group of animals with transplanted tumors and the mean ± SD of three mice for healthy animals. The asterisks indicate a significant difference between groups (* p < 0.05).