Table 2.
Renal function and renal replacement therapy.
| Renal Function During Sample Collection | Samples (n = 288) |
|---|---|
| eGFR (CKD-Epi) (mL/min/1.73 m2), median (IQR) | 81 (41–101) |
| CrCL (Cockcroft-Gault) (mL/min), median (IQR) | 83 (47–118) |
| Serum creatinine concentration (mg/dL), median (IQR) | 0.91 (0.66–1.52) |
| Urea concentration (mg/dL), median (IQR) | 51 (34–97) |
| Measured 24 h clearance (mL/min), median (IQR), n = 190 | 63 (23–101) |
| Number of samples while ARC (based on CKD-Epi), n (%) | 94 (33) |
| Number of samples on CVVH, n (%) Fluconazole concentration (mg/L), median (IQR) Fluconazole dose (mg), median (IQR) Fluconazole dose (mg/kg), median (IQR) |
37 (13) 14.9 (7.4–17.5) 800 (400–800) 6.7 (5.8–10.3) |
| Number of samples on IHD, n (%) | 9 (3) |
IQR: interquartile range; eGFR: estimated glomerular filtration rate; CrCL: creatinine clearance; ARC: augmented renal clearance; CVVH: continuous venovenous hemofiltration; IHD: intermittent hemodialysis.