Figure 1.

Study Design. Overweight and obese (OVOB) and lean participants were recruited prior to the first visit (Fasted Visit), where an oral glucose tolerance test (OGTT) (75 g) was administered in the fasted state. The OVOB participants returned approximately a week later for an OGTT (50 g) in a random fed state (Random-Fed Visit). Blood samples were collected before and during the OGTT and used for glucose, insulin, and untargeted metabolomics assays. Mean age and range of ages reported (years).