Table 1.

Characteristics of study participants at the Fasted Visit, stratified by weight group. Significance denoted with unadjusted p-value < 0.05 (bolded).

Categorical Variables	OVOB	Lean	p -Value 1
	n (%)	n (%)
sex
Male	97 (43%)	26 (47%)	0.5254
Female	131 (57%)	29 (53%)
race
Asian/Pacific Islander	4 (2%)	4 (7%)	0.1745
African American/Black	59 (26%)	12 (22%)
White	135 (59%)	32 (58%)
more than one race	19 (8%)	6 (11%)
did not wish to report	11 (5%)	1 (2%)
ethnicity
Hispanic	18 (8%)	5 (9%)	0.7707
non-Hispanic	210 (92%)	50 (91%)
abnormal 2-hr plasma glucose (≥140 mg/dL)
Yes	16 (7%)	3 (5%)	0.6776
No	212 (93%)	52 (95%)
abnormal fasting plasma glucose (≥100 mg/dL)
Yes	8 (4%)	1 (2%)	0.5213
No	220 (96%)	54 (98%)
ADA prediabetes (FPG≥ 100 mg/dL or 2-hr PG ≥ 140 mg/dL or HbA1c ≥ 5.7%)
Yes	35 (15%)	6 (12%)	0.4009
No	193 (85%)	49 (88%)
Continuous Variables	OVOB	Lean	p -Value 2
	Mean (SD)	Mean (SD)
age (years)	12.9 (2.5)	13.0 (2.6)	0.7301
BMI percentile	95 (4)	59 (27)	7.52 −14
HOMA-IR	5.13 (2.99)	2.80 (1.21) 3	4.53 −8
HbA1c	5.2 (0.3)	5.1 (0.3) 3	0.2082
fast time (hours)	14.0 (1.3)	14.1 (1.4)	0.7606
fasting OGTT response
glucose (t0) (mg/dL)	84 (8)	85 (8)	0.7475
glucose (t30) (mg/dL)	126 (22)	132 (25)	0.1119
glucose (t60) (mg/dL)	112 (29)	117 (26)	0.2182
glucose (t90) (mg/dL)	107 (26)	106 (21)	0.6263
glucose (t120) (mg/dL)	102 (24)	98 (22)	0.2562
insulin (t0) (µU/mL)	24 (14)	13 (5) 3	1.55 × 10−8
insulin (t30) (µU/mL)	194 (132)	112 (72)	4.09 × 10−9
insulin (t60) (µU/mL)	156 (117)	87 (53)	7.04 × 10−10
insulin (t90) (µU/mL)	145 (126)	80 (56)	2.69 × 10−8
insulin (t120) (µU/mL)	133 (117)	65 (57)	2.42 × 10−9
AUC glucose	3121 (2112)	3294 (1711)	0.5228
AUC insulin	17,223 (11,206)	9648 (5468)	1.33 × 10−11

¹ Represents Pearson’s chi-square test for categorical variables. ² Represents unpaired t-test for continuous variables. ³ n = 54.