| ADT | androgen deprivation therapy; |
| AML | acute myeloid leukemia; |
| AKT/PKB | protein kinase B; |
| AR | androgen receptor; |
| ARE | androgen response element; |
| ASK1 | apoptosis signal-regulating kinase; |
| BAT | bipolar androgen therapy; |
| CRPCa | castration-resistant prostate cancer; |
| CSPCa | castration-sensitive prostate cancer; |
| DAB2IP | disabled homolog 2-interacting protein; |
| HSP | heat shock protein; |
| LBD | ligand binding domain; |
| MEFs | mouse embryonic fibroblasts; |
| mTOR | mammalian target of Rapamycin; |
| mTORC1/2 | mTOR complex 1/2; |
| PCa | prostate cancer; |
| PDK1 | phosphoinositide-dependent kinase 1; |
| PH | pleckstrin homology; |
| PI3K | phosphatidylinositol-3-kinase; |
| PI(4,5)P2 | phosphatidylinositol-4,5-biphosphate |
| PI(3,4)P2 | phosphatidylinositol-3,4-biphosphate |
| PIP3 | phosphatidylinositol-3,4,5-triphosphate |
| PSA | prostate-specific antigen; |
| RTK | receptor tyrosine kinase; |
| p70S6K | p70S6 kinase; |
| SAL | supraphysiological androgen level; |
| SHIP1/2 | Src homology 2 domain containing inositol polyphosphate 5-phosphatase 1/2 |