TABLE 1.

Precision and reproducibility of Cobas-AM

Sample no.	Input HBV DNA (copies/ml)	Technician 1				Technician 2
		Meana (copies/ml)	Rangea (copies/ml)	CV (%)	Within-run CV range (%)	Meana (copies/ml)	Rangea (copies/ml)	CV (%)	Within-run CV range (%)
3	200	258	128–495b	50	25–85	317	201–756b	57	19–84
4	400	544	123–1,030	45	18–97	666	115–948	34	7–64
5	825	1,064	425–2,400	50	18–79	1,562	885–2,060	28	12–33
6	1,650	2,067	1,100–3,360	33	5–35	2,600	2,060–3,210	15	10–21
9	13,300	15,525	10,400–24,000	23	10–16	21,400	17,600–29,000	14	3–22
12	106,000	97,575	75,100–128,000	16	7–19	121,335	95,000–143,000	12	4–17

^aOf 20 analyses; quadruplicates of each sample were analyzed repeatedly over 5 days by each technician. 

^bTwo nonreactive results of analyses are excluded.