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. 2021 Oct 15;19(10):577. doi: 10.3390/md19100577

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Interaction of the 2O-sulphated fucooligosaccharide with the neutralising orthohantavirus antibody epitope of the integrin β3. (A) Docking of 2O-sulphated fucooligosaccharide onto the integrin β3 epitope for the neutralising antibody (integrin β3 residues 177–184). (B) Electrostatic potential of the integrin β3 antibody-binding site. Electropositive potential is shown in blue and electronegative potential is shown in red. (C) Two-dimensional (2D) diagram of contacts of fucooligosaccharide at the integrin β3 binding site.