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mRNA expression of IFNγ, TNFα, IL-1β and IL-6 in PBMCs or monocytes treated with LPS. Cells were incubated with LPS (100 ng/mL) only or in presence of TLR4 inhibitor (inhTLR4); peptides: N1, N2, 17.1, 17.1A for 12 h. All values were normalized to control (before any treatment). Level of mRNA measured by RT-PCR, using RPLP0 and GADPH as references. (one-way ANOVA, p-value ◊ < 0.05 vs. untreated; t-test, p-value *** < 0.005; one-way ANOVA, p-value: ** < 0.05, * < 0.01 vs. LPS).
